Forging friendships with women can be frightening, to some extent. You’ll have to deal with catfights, hissy fits, and monthly hormone-induced meanness. But there’s still a lot of things that make having a solid female best friend worth it. She will empathize with your bouts of PMS, update you on the latest gossip, gamely help you get over breakups, and, best of all, willingly accompany you on your shopping trips. And let’s admit it: our BFFs will always be way better at listening, caring, and consoling than our guy buddies can ever be.

To celebrate female camaraderie, we’re presenting you with a list of some of our favorite silver screen BFFs. The ladies on our list redefined the meaning of friendship for us, proving that no amount of bad guys or unfortunate events should ever get in the way of our love for our gal pals. See our list below.